Video games in 2025: puzzles galore
<p>I played more games this year, particularly puzzle games. I also just bought a Switch 2, which seems good so far (nice screen).</p> <h1 id="puzzle-games">Puzzle games</h1> <h2 id="blue-prince"><em>...
Christmas dinner
<p>Mostly for personal reference for next year, here were my xmas dinner notes. I forgot about stuffing, and didn’t make yorkshire puddings properly because our main oven is broken (we have a co...
Brief thoughts on: iNaturalist
Let me say first: I was wrong! My profile shows that I created my account at iNaturalist in August 2008, the year that the site was launched. I created a lot of accounts in those days. At the time, th...
We predict that the transcript abundance from the gene we are knocking down will (checks notes) decrease
The problem with gene-wise characterization of genetic interventions...
Mean squared error for estimates of differential expression
Bias-variance tradeoffs for virtual cell evals are weird...
Thoughts on generative AI contributions as an Open Source project maintainer
<p>To be clear up front, these are my personal opinions right now, and while they will influence any future policy I have a hand in writing, they are not the position of the Biopython Project or the O...
Making a map of the locations where bacterial isolates were collected
<p> I wanted to make a map of the locations in the world were some bacterial isolates were collected. I found a <a href="https://r-spatial.org/r/2018/10/25/ggplot2-sf.html">nice website</a>&...
Submitting V. cholerae and MLST sequence types to PubMLST
<p> I've been submitting novel <i>Vibrio cholerae </i>MLST alleles and sequence types to the <a href="https://pubmlst.org/">PubMLST</a> database.</p><p>This is the <a href="https:/...
Using R/anomalize to identify delays in games of Australian Rules football
In which we generate a dataset of game durations, do a little exploratory data analysis and then try to identify unusual instances and their causes. In my Twitter-whinge-post, I mentioned that one of ...
Brief thoughts on: the slow death of Twitter
Why am I still there? I joined Twitter (I will never say ‘X’), unbelievably, in March 2008. I was sceptical of “microblogging” at the time but in those days, I was willing to t...