Our journey through low-complexity regions
<p>Those who inspect SVs often have probably noticed many SVs fall in low-complexity regions (LCRs) or tandem repeats and they are challenging to call. How many and how challenging? I could not find a...
Analyzing ICE Arrest Data - Part 2
In this blog post, I continue to demonstrate how to analyze publicly available datasets related to U.S. Immigration and Customs Enforcement (ICE). This time, I take advantage of publicly available dat...
Do not repeat yourself: List column to do RNAseq differential expression analysis
<p><strong>To not miss a post like this, sign up for my <a href="https://divingintogeneticsandgenomics.ck.page/profile">newsletter</a> to learn computational biology and bioinformatics.</strong></p> <...
Benchmark update: metaMDBG and Myloasm
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Zbąszyń
The mathematician Carl Friedrich Gauss invented the heliotrope for long-distance surveying in 1821. Just a year later, he proved that least squares regression provided the BLUE estimator for data with...
Back to Writing: Some Thoughts on Machine Learning
<p>Hello. Finally, I’m back to writing on the blog. Intense work commitments and plenty of unexpected events have limited the time I could spend studying and sharing with you my progress in the world ...
A quick look at Roche's SBX
<p><a href="https://sequencing.roche.com/us/en/article-listing/sequencing-platform-technologies.html">Sequencing by Expansion (SBX)</a> is Roche’s new short-read sequencing technology. Roche released ...
Cross-sample homopolymer polishing with Pypolca
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On professionalism
<p>I'm a huge fan of Conan O'Brien; there's just something about his demeanour, humour, and wittiness that I admire. I discovered him on YouTube around 2012 and was quite oblivious to who he was, what...
Reproducible Computing in Bioinformatics: Lessons from My Latest Talk
<p>Hey everyone, it’s Tommy here. If you’ve been following my blog or my Twitter/X (<span class="citation">@tangming2005</span>), you know I love diving into the practical side of bioinformatics and g...