Tracing 700 million years of cell evolution
RNA sequencing combined with AI helps Unify compare cell types across distant species by identifying shared biological functions even when individual genes no longer directly......
How should biological replicates be handled in long-read RNA sequencing?
Long-read RNA sequencing analysis shows that handling biological replicates differently can influence transcript reconstruction and the discovery of novel RNA isoforms......
RNA-Seq reveals a new way the developing heart controls its growth
Single-cell RNA sequencing reveals how lymphatic-derived Reelin influences epicardial cells, fibroblasts and growth signaling involved in heart development and potentially cardiac repair......
Nanopore direct RNA sequencing reveals the challenges of detecting RNA modifications
RNA molecules are not simply copied from DNA and sent directly to make proteins. They can also undergo chemical modifications that influence how they are processed, stabilized and used inside cells. C...
The Human RNome Project Consortium seeks to publish first-ever complete sequence of the body’s RNA
Brown professor Vivian Cheung is one of the founding members of the consortium. The Human Genome Project was a 13-year effort to generate the first ever complete sequence of all human DNA, widely rega...
September 2026 links
Thomas Jefferson, biosecurity, AI, creativity, peer review, academic life & discourse...
What Instrument Protocol Did I Actually Use?
Puttering around with some ideas for future experiments on our autonomous lab, I realized a potential software engineering gap that in my very hot take is ubiquitous in the industry. For complex inst...
A Guide for Biologists on Quickly Mastering Machine Learning and AI Concepts - (iii)
<p>Alright class ! If you are still here, you already completed <a href="https://homolog.us/blogs/bioinfo/2026/09/24/guide-biologists-quickly-mastering-machine-learning-ai-concepts-i/">part (i)</a> co...
What About BOB-Seq?
<a href="https://sculpta.bio/preprint">An interesting new approach to short read RNA-Seq library preparation </a>bobbed into view this week, using click chemistry to barcode samples before any enzymat...
My relationship with AI is changing
When the facts change, I change my mind. What do you do, sir?...