MUTE-Seq – ultrasensitive method to detect low-frequency cancer mutations
MUTE-Seq enriches rare cancer mutations by removing wild-type DNA, enabling highly sensitive detection that enhances liquid biopsy.....
Pancreatic tumors plan their travels
Researchers show pancreatic tumors adopt organ-specific cellular states early on, revealed through single-nucleus RNA sequencing, offering new clues for predicting metastatic sites and guiding targete...
Quoting the Resonant Computing Manifesto
Five principles for the future of computing: private, dedicated, plural, adaptable, and prosocial....
Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains
RNA sequencing reveals how tumor stem cells reprogram neutrophils through prostaglandin signaling, creating a protective niche that limits immunotherapy effectiveness......
Pan-cancer gene set discovery via scRNA-seq for optimal deep learning based downstream tasks
Machine learning has become a powerful tool for cancer research, but it depends heavily on the quality of the data that is used to train it. RNA sequencing data can contain information on thousands of...
Single cell RNA-seq uncovers breast cancer diversity
Breast cancer is made up of many different types of cells, and these differences can strongly influence how a tumor grows and responds to treatment. A research team from the Henan University of Chines...
The False Choice Between Meaning and Accountability in Higher Education
Thoughts on Ronald Purser's December 2025 essay in Current Affairs, "AI is Destroying the University and Learning Itself"...
The "If-Then" Approach to AI Biosecurity
A Measured Approach to AI+Biosecurity: The "If-Then" Framework from the 2025 NASEM report, The Age of AI in the Life Sciences: Benefits and Biosecurity Considerations....
Quoting Kevin Roose (NYT / Hard Fork)
I'm not going to listen to opinions about AI from people who don't use AI....
We predict that the transcript abundance from the gene we are knocking down will (checks notes) decrease
The problem with gene-wise characterization of genetic interventions...