Bioinformatics Blogs

scKGBERT – a knowledge-enhanced foundation model for single-cell transcriptomics

From RNA-Seq Blog – Wed, 26 Nov 2025 16:02:19 +0000

scKGBERT combines large scale RNA sequencing data with protein interaction networks to improve biomarker discovery and cell characterization for precision medicine......

RNA-Seq reveals how brain protein OTULIN controls tau expression and could transform Alzheimer’s treatment

From RNA-Seq Blog – Wed, 26 Nov 2025 16:02:05 +0000

Researchers reveal OTULIN as a key regulator of tau production and RNA sequencing signatures in neurons, uncovering new therapeutic opportunities for Alzheimer’s disease and related tauopathies......

Lexogen and Ochre Bio advance large-scale RNA sequencing to accelerate functional genomics and RNA therapy discovery

From RNA-Seq Blog – Wed, 26 Nov 2025 16:01:50 +0000

Lexogen and Ochre Bio generated large-scale functional genomics data from human hepatocytes, delivering high-fidelity RNA sequencing to advance AI-driven target......

Weekly Recap (Nov 26, 2025)

From Paired Ends (Stephen Turner's blog) – Wed, 26 Nov 2025 10:51:13 GMT

R updates (R Data Scientist, R+AI conference, R weekly), Claude 4.5 Opus, Genesis Mission, AI+science, AI updates (Posit, AI Data Scientist), missing heritability, AI+edu, biotech, AIxBio, new papers...

A DNA search engine

From RNA-Seq Blog – Tue, 25 Nov 2025 12:30:00 +0000

Computer scientists at ETH Zurich have developed a digital tool capable of searching through millions of published DNA records in a matter of seconds. This can significantly accelerate research into a...

Helixer: ab initio prediction of primary eukaryotic gene models

From RNA-Seq Blog – Tue, 25 Nov 2025 12:29:33 +0000

Understanding where genes are located within a genome is a critical part of biology, because genes act as the instruction manual for how organisms grow, function, and adapt. Yet as scientists sequence...

The Genesis Mission

From Paired Ends (Stephen Turner's blog) – Tue, 25 Nov 2025 09:37:12 GMT

An AI Manhattan Project for Science and Biotech...

Weekly Recap (Nov 21, 2025)

From Paired Ends (Stephen Turner's blog) – Fri, 21 Nov 2025 10:39:56 GMT

R updates (R Data Scientist, R weekly)...

Labels for Clear Feedback in Peer Review

From Paired Ends (Stephen Turner's blog) – Mon, 17 Nov 2025 23:54:39 GMT

Conventional Comments provides a framework for offering clear and actionable feedback in peer review...

Weekly Recap (Nov 14, 2025)

From Paired Ends (Stephen Turner's blog) – Fri, 14 Nov 2025 11:05:10 GMT

posit::conf(2025) & Nextflow Summit talks, bioRxiv+medRxiv AI reviews, R updates (R Data Scientist, R weekly), Claude Scientific Skills, Python package development for R users, new papers & preprints...