Where did BWA come from?
<p>My blog posts are often motivated by casual conversations with other scientists. This blog post is an example. Someone asked me how I thought of using a compression algorithm for alignment in <a hr...
Speeding sourmash the heck up
<p>Faster things are always nice, right?</p>...
Speeding sourmash the heck up
<p>Faster things are always nice, right?</p>...
BLAST max-target-seq meets metabarcoding
<p>This is my first blog post in years - primarily down to a second child who is now a toddler. And what better topic to return to than a mainstay of past content, NCBI BLAST? This time with a motivat...
Multiple horses for multiple courses
<p>This post is about a talk I gave in February 2020 at <a href="https://rslondon.ac.uk/rslondonse-2020/">RSLondonSouthEast</a>, a local conference for research software engineers. First an overview o...
Graph-based gene prediction with ggCaller
<div> <nav id="TableOfContents"> <ul> <li><a href="https://www.bacpop.org/blog/index.xml#the-bacterial-pangenome--quantifying-within-species-diversity">The bacterial pangenome – quantifying within-...
Observations about Helicos, a single molecule sequencer from 2008
Take a look at the latest blog post from Dale Yuzuki, published on the Silent Valley Consulting website, about a technology from 2008 to 2011 that was the world’s first “true single molecu...
Silent Valley Consulting – open for business
Life sciences marketing consulting for technical writing, content marketing, strategy and market research Several years ago during the publishing of the book about COVID-19 diagnostics, therapeutics a...
Introducing kyber: minimalistic quality assessment plot for long reads
<p>I am releasing kyber today, and you can find all about it on <a href="https://github.com/wdecoster/kyber">GitHub</a>.</p> <p>In short, kyber produces a heatmap showing where the majority of your re...
Announcing Phasius for visualization of phase blocks
<p>Long-read sequencing enables the phasing of variants and reads, i.e., separating those into two parental haplotypes. Without trio information, you will not be able to say which variant is inherited...